Review on how PMN functions are negatively regulated by immune signaling pathways.

The truncated isoform of the neurokinin 1 receptor generated through alternative splicing regulates several biologic functions which include immune and inflammation pathways.

Review on SHIP's role in mast cell and macrophage activation in vitro, in the SHIP^−/− mouse, and human immune-mediated diseases.

Review on the role of the PI3K/AKT pathway in regulatory T cell development and function, with a focus on pathologies associated with impaired PI3K signaling.

Review of the canonical and non-canonical functions of FcγRIIB and its potential as a therapeutic target for immunotherapy of cancer and autoimmune disorders.

Review of how TRAF3 both promotes and restrains inhibitory signaling to B and T lymphocytes by cytokine and antigen receptors.

Review on the fine-tuning of IFN signaling by negative regulators of the IFN production and response.

Review of innate immune regulation in both cancer and autoimmune disease pathogenesis, with a focus on the function and regulation of type 1 IFN responses.

Review of regulators that negatively modulate NF-κB signaling to attenuate inflammation and promote resolution.

Review of checkpoint proteins' contributions to immunological signaling in shock and sepsis.

Review on recent advances in our understanding of the mechanisms that negatively regulate NLRP3 inflammasome activation.

Review of key molecular and cellular negative regulators of inflammation within the immune privileged eye.

Review on STING's role and regulation in immunity against tumors and certain viruses.

Review on select leukocytic functions and how they are regulated by the anti-inflammatory protease, activated protein C.

Review on role miRNAs in innate immunity as well as mechanistic pathways regulated by key miRNAs.

Review on the mechanisms by which IFN-gamma manifests paradoxical functions of relevance to developing highly tailored immunotherapeutics for cancer patients.

USP18 promotes HIV-1 replication by negatively regulating expression of antiviral genes induced by T1 IFN signaling.